The EU-OPENSCREEN Baltic Symposium on Chemical Biology on Monday, May 25, 2020, discussed with researchers from the Riga Technical University, Riga Stradiņš University, University of Latvia, Institute of Organic Synthesis, Vilnius University, Kaunas University of Technology, and the Latvian Ministry of Education and Science during the EU-OPENSCREEN Baltic Symposium on Chemical Biology. The virtual symposium was organised by Professor Osvalds Pugovičs at our EU-OPENSCREEN partner site Latvian Institute of Organic Synthesis (OSI) in Riga, Latvia. Dr. Bahne Stechmann, EU-OPENSCREEN, explained how EU-OPENSCREEN facilitates working in partnership in Chemical Biology and early drug discovery across Europe. Professor Päivi Tammela, University of Helsinki, and Dr. Edgar Specker, Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) in Berlin, presented the EU-OPENSCREEN academic compound library and the concept for the donation of compounds. We thank all participants for the fruitful discussions.