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EU-OPENSCREEN compound collection in the press!

We congratulate our partners at Fraunhofer ITMP on their latest publication in ACS Pharmacology & Translational Science: "Thiol-Reactive or Redox-Active: Revising a Repurposing Screen Led to a New Invalidation Pipeline and Identified a True Noncovalent Inhibitor Against Papain-like Protease from SARS-CoV-2"

 

 

In this publication, our colleagues from our screening partner site ITMP Fraunhofer, Maria Kuzikov, Jeanette Reinshagen, Philip Gribbon, Storici Paola, Andrea Zaliani report on an effort to identify and validate inhibitors of SARS-CoV-2 papain-like protease PLpro activity. They utilized three repurposing libraries for this study, including the EU-OPENSCREEN bioactives collection. Please read the full publication here:  

Read the full text here: https://pubs.acs.org/doi/10.1021/acsptsci.4c00325