What is ISIDORe?
ISIDORe is an EU-funded project under the Horizon Europe program that unites a multidisciplinary consortium of 17 European research infrastructures to offer integrated services for combatting current and future infectious disease outbreaks. It is coordinated by our partner research infrastructure ERINHA. ISIDORe brings together more than 150 European service providers from 32 countries and a total funding of €21 million. The project provides access to key services to support projects for the study of SARS-CoV-2, its variants and other potential pathogens. ISIDORe is part of the EU-Commission´s biodefense preparedness plan, the Health Emergency Preparedness and Response Authority (HERA) Incubator. Considering its structure, it represents a meta-infrastructure project of unprecedented dimensions in the European Research Area and serves as a central instrument in the European R&D response to epidemic outbreaks.
You can read more about the launch of Europe's Integrated Services For Infectious Disease Outbreak Research here: https://www.nature.com/articles/d41586-022-00669-4
What is EU-OPENSCREEN´s involvement in ISIDORe?
EU-OPENSCREEN ERIC as the European Research Infrastructure Consortium for chemical biology and early drug discovery leads a transnational access work package dedicated to diagnostic and therapeutic discovery services. EU-OPENSCREEN screening and chemistry partner sites offer drug discovery and early preclinical development services to external researchers in academia and industry working on new therapeutics against SARS-CoV-2 variants and epidemic-prone pathogens. Activities range from assay development and validation of preliminary research results, to HTS hit discovery programs using high throughput in vitro biochemical and cell-based assays to further progress promising small molecules to lead development and candidate nomination stage.
Moreover, EU-OPENSCREEN teams up with European partners that offer access to antibody and nanobody discovery platforms, and to services related to the development of in vitro diagnostic tests. The overall aim is to build and integrate an efficient and fast service platform that accommodates the broad demands of users seeking small molecule and antibodies therapeutics as well as diagnostic solutions.
Who is participating?
In ISIDORe diagnostic and therapeutic discovery services will be provided by a network of multiple access providers:
Open calls to access EU-OPENSCREEN facilities, antibodies discovery platforms and diagnostic services will be announced on our webpage. Information about our screening and chemistry partners can be found at https://www.eu-openscreen.eu/services/screening.html and https://www.eu-openscreen.eu/services/medicinal-chemistry.html, respectively.
Read more here.
How can you contact us if you wish to collaborate with us, or would like to get more information on the ISIDORe project?