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In the following, we will highlight in special "sucess stories" the progress of these projects.
Phenotypic screening for novel antibiotics targeting Mycobacterium tuberculosis
Targeting SMAD4, a transcription factor protein mutated in tumours and rare diseases
Interfering with RAN translation in ALS – An extensive screening campaign with high-quality laboratory practices
Identification of the Pharmacological Target of Compounds Modulating the Activity of the Cellular Prion Protein (CHEMPRION)
By leveraging EU-OPENSCREEN services, Marcin was able to utilise advanced MALDI-MSI technology to visualise the metabolic alterations induced by OATD-02.
Screening of European Chemical Biology Library revealed small molecules which inhibit a mitochondrial enzyme involved in Alzheimer’s disease
Cooperation between Fabra University in Spain, HZI in Germany and Masaryk University in Czech Republic conducted a screening under BSL3 conditions with exceptional efficiency.