canSERV

Funding programme: Horizon Europe (Project ID 101058620)

Budget: €14.8 Mio

Coordinator: BBMRI-ERIC

Start date: 01 September 2022

End date: 31 August 2025

Project website: https://www.canserv.eu/

Aim of the canSERV project

canSERV aims to accelerate the process of translating theoretical knowledge into personalised oncology clinical practice, which will give cancer patients faster and easier access to solutions and products.The project is aligned to the EU Cancer Mission declared by the European Commission suggesting that taking interdisciplinary approaches could be the key to accelerating cancer research and finding new treatment options. The canSERV project responds to this by providing new interdisciplinary and customised oncology services across the entire cancer continuum. This will provide a comprehensive portfolio of oncology-related research infrastructure services available to all EU member countries and beyond. The range of services offered by the consortium of life science research infrastructures is available through a single catalogue and intuitive user-friendly transnational access (TNA) process.

What is EU-OPENSCREEN offering within the canSERV project?

EU-OPENSCREEN leads WP4 on new therapeutic solutions providing access to drug discovery expertise and state-of-the-art services to identify novel therapeutic solutions for innovative personalised cancer research. In particular, partner sites will provide in WP4 access to HTS target-based and phenotypic assays, using biochemical or cell-based assays, incl. 3D spheroids assays, and to hit expansion and medicinal chemistry support to progress projects towards validated hit and lead stages.

In WP2 Advanced Technologies for understanding tumour biology and for personalised oncology EU-OPENSCREEN partners will support the development of disease-relevant assays (biochemical, pathway-based and cell-based 2D or 3D) for compound screening or hit validation, high-content image-based profiling of compounds, including those applied on patient-derived cells and the validation of the binding affinity and kinetics of compounds towards the drug target via biophysical methods and, and preclinical evaluation in ADME-tox assays of selected lead compounds (developed within WP4).

In addition EU-OPENSCREEN contributes with expertise and capacities to WP3 access to cutting-edge and high-quality services that will support the optimization of existing screening programmes, the advancement of novel approaches for screening and early detection, identification of new biomarker sets, as well as will contribute to the development of novel therapeutics based on molecular predictors ensuring the metabolomic profiling of cancer stem cell-derived exosomes.

Get funding for your project within canSERV:

Call for Transnational Service Provision

Under the new canSERV Open Call researchers are welcome to apply to the portfolio of services offered by canSERV to address the research needs of the entire oncology developmental pipeline. 

Your research project

• Can vary from basic discovery science to translational science and translation into personalised oncology.
• Is expected to address at least one of the four strategic goals of the Cancer Mission (understanding of cancer; prevention and early detection; diagnosis and treatment; quality of life for patients and their families).
• Can benefit from requested services, taking into account that your requested services must be finalised by the end of May 2026. Please keep this in mind when filling out the application form, particularly when outlining your project timeline and the use of the requested services.

Overall budget: 1.500.0000 EUR

Submission deadline: 15 July 2025, 2 pm CEST

For more information please see the canSERV website: https://www.canserv.eu/calls/open-call-for-transnational-service-provision/

Contact us via our EU-OPENSCREEN helpdesk if you need advice on how you can collaborate with us within the canSERV Open Call.