University of Helsinki,
Phone: +358 50 448 0886
Efflux inhibitors, cell-based screens, assay development
Assay development and screening, bioreporters, cell- and target-based assays. The Bioactivity Screening Group at the Faculty of Pharmacy, University of Helsinki, focuses on enhancing antimicrobial drug discovery – covering aspects from early target validation to detailed characterisation studies of novel antimicrobial substances. We are a specialist screening site in EU-OPENSCREEN ERIC and a partner in the JPIAMR project RESET-ME (2019-2022), focused on restoring the E. coli sensitivity for antibiotics by blocking TolC-mediated efflux.
Development of tools and approaches for antibacterial screening, using both target- and cell-based screening assays, and thus enhancing the discovery of novel antibacterial agents.