Welcome to ECBS 2008

July 10–11, Barcelona, Spain

The European Chemical Biology Symposium (ECBS 2008), held in Barcelona on 10–11 July 2008, was one of the early European meetings dedicated specifically to the emerging field of chemical biology. Organized jointly by the Barcelona Science Park (Parc Científic de Barcelona, PCB) and the Municipal Institute for Medical Research (IMIM-Hospital del Mar), the symposium aimed to bring together researchers working at the intersection of chemistry, biology, bioinformatics, and drug discovery.

At the time, chemical biology was rapidly gaining momentum as a highly interdisciplinary research area. The meeting reflected this development by focusing on topics such as chemical libraries, screening technologies, chemoinformatics, molecular probes, and the application of small molecules to study biological systems. ECBS 2008 also highlighted the growing importance of academic drug discovery initiatives and collaborative research infrastructures emerging across Europe.

The symposium took place across two major research venues in Barcelona — the Parc Científic de Barcelona and the Barcelona Biomedical Research Park (PRBB) — both of which were becoming important hubs for biomedical and translational research in Southern Europe. Internationally recognized scientists including Alex Levitzki and Ronald Frank contributed keynote lectures, underlining the conference’s ambition to position European chemical biology within a broader international context.

In retrospect, ECBS 2008 can be seen as part of a broader wave of interdisciplinary life-science conferences in Europe during the late 2000s, when systems biology, chemical biology, and high-throughput screening technologies increasingly converged. The event helped establish a network and discussion platform that later evolved into the recurring ECBS conference series.

Schedule 2008

Thursday, July 10th
08:00
Registration
09:30
Official ECBS Symposium Opening
10:00
ECBS Symposium Opening Talk – Keynote Address
New classes of Protein kinase inhibitors
Alexander Levitzki, The Hebrew University of Jerusalem, Israel
10:45
Coffee Break
Session 1: Protein‑Protein Interactions
11:15
Protein‑protein interaction inhibitors of transcription factors and kinases
Thorsten Berg, Max Planck Institute of Biochemistry, Martinsried, Germany
11:45
Targeting Protein‑Protein Interactions in the Brain
Kristian Strømgaard, University of Copenhagen, Denmark
12:15
Protein‑Protein Interactions in Apoptosis: the Smac‑XIAP Example
Pierfausto Seneci, CISI and University of Milan, Italy
12:45
Polymerase Subunit Interaction Inhibitors as Antiviral Agents
Ulrich Kessler, PiKe Pharma GmbH, Zürich, Switzerland
13:15
Lunch
Session 2: Chemical Tools and Approaches to Investigate Biological Pathways / Targets (I)
15:00
Novel deorphanisation strategies based on academic screening
Marcel Hibert, Université Louis Pasteur de Strasbourg, France
15:30
Targeting Telomerase: Innovative approaches for bioactive compounds discovery in academia
Gerardo Turcatti, EPFL School of Life Sciences, Lausanne, Switzerland
16:00
Silver Bullet or Golden Hammer: Drug Target Specificity Profiling by Chemical Proteomics
Uwe Rix, CeMM – Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria
16:30
Coffee Break
Session 3: Chemical Tools and Approaches to Investigate Biological Pathways / Targets (II)
17:00
Chemical tools for the validation of protein targets generated by dynamic ligation screening
Jörg Rademann, Leibniz‑Institut für Molekulare Pharmakologie (FMP), Berlin, Germany
17:30
Bioprospecting in Cyanobacteria: Reverse Chemical Genetics Using Natural Products
Karl Gademann, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland
18:00
Histone Acetylation and Methylation as Drug Discovery Targets
A. Ganesan, University of Southampton, United Kingdom
18:30
Chemistry driven drug discovery in the kinase inhibitor field
György Kéri, Semmelweis University and Vichem Chemie Research Ltd., Budapest, Hungary
21:00
ECBS 2008 Symposium Dinner
Friday, July 11th
Session 4: New Integrative Tools in Chemical Biology
09:00
Implementing Information Management in Academia
Damiano Banfi, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland
09:30
Key Aspects for the Compilation of a Comprehensive Chemical Biology and Drug Discovery Screening Collection
Edgar Jacoby, Novartis Institute for Biomedical Research, Basel, Switzerland
10:00
Ligand Efficiency Indices for an Effective Mapping of the Chemico‑Biological Space
Cele Abad‑Zapatero, Center for Pharmaceutical Biotechnology, University of Illinois at Chicago, USA
10:30
Navigating through the Chemo‑Target Space
Jordi Mestres, Grup Recerca Informàtica Biomèdica, Institut Municipal d’Investigacions Mèdiques (GRIB‑IMIM), Barcelona, Spain
11:00
Coffee Break
Session 5: Chemical Biology in Europe
11:30
Introduction
Walter Rosenthal, Leibniz‑Institut für Molekulare Pharmakologie (FMP), Berlin, Germany
11:40
Drug Discovery at Dundee
Stuart McElroy, Scottish Hit Discovery Facility, University of Dundee, Scotland
12:00
ChemBioNet: HTS on Academic Platforms
Jens Peter von Kries, Leibniz‑Institut für Molekulare Pharmakologie (FMP), Berlin, Germany
12:20
Scandinavian Chemical Biology Initiative
Kjetil Taskén, The Biotechnology Centre of Oslo, Norway
12:40
Chembiobank: Building an Annotated Molecular Library in Spain
Jordi Quintana, Parc Científic de Barcelona (PCB), Barcelona, Spain
13:00
ECBS Symposium Closing Talk – Keynote Address
Chemical Biology of the tumor suppressor p27kip
Ronald Frank, Helmholtz Centre for Infection Research, Braunschweig, Germany
13:45
Official ECBS Symposium Closing
14:15
Lunch