EU-OPENSCREEN - AUTUMN TRAINING SCHOOL 2021

We are happy to present this year's edition of our online autumn training school 2021. 

Participation fee: free of charge

Registration deadline: November 8th 2021

This autumn school receives funding from the European Union´s Horizon 2020 research and innovation programme under grant agreement No 823893 (EU-OPENSCREEN-DRIVE).

Topics

This first edition of our training school will present various aspects of chemical biology

Starting with a general introduction to the field, we will continue by exploring more specific subjects such as

  • hit selection,
  • cheminformatics,
  • medicinal chemistry,
  • principles of open data and open source tools,
  • assay development and optimisation,
  • data analysis.

New services of EU-OPENSCREEN ERIC such as fragment screening and chemoproteomics will also be presented. Additionally, our speakers will introduce you to the EU-OPENSCREEN ERIC European Chemical Biology Database (ECBD), compound libraries and specific instruments which are used during compound management and screening campaigns.

Schedule

Monday - November 15, 2021

Welcome and Introduction

9:00 - 9:30

EU-OPENSCREEN ERIC Screening and Medicinal Chemistry Services

Wolfgang Fecke 

Director General EU-OPENSCREEN ERIC, Coordinator EU-OPENSCREEN-DRIVE

1st Session

09:30 - 10:45

General introduction to chemical biology

Mabel Loza and Maria Joao Matos

University of Santiago de Compostela (USC), Spain

10:45Break (15')

2nd Session

11:00 - 12:15

Assay development and optimization

Pepo Brea

Head of HTS Unit - University of Santiago de Compostela (USC), Spain

12:15Lunch Break (105')

3rd Session

14:00 - 15:15

Compound libraries

Jordi Mestres

IMIM, Spain

 

Tuesday - November 16, 2021

1st Session

09:30 - 10:45

Hit selection

Johannes Landskron

Norwegian Center for Molecular Medicine (NCMM) at Oslo University (UiO), Norway

10:45Break (15')

2nd Session

11:00 - 12:15

Lead optimisation and candidate selection

Sheraz Gul

Head of Assay Development and Drug Repurposing, Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Germany  

12:15Lunch Break (105')

3rd Session

14:00 - 15:15

Instruments / equipment

Sophie Masin (Brusseau)

Laboratory Automation Manager - EU-OPENSCREEN ERIC, Germany

 

Martin Neuenschwander

Screening Unit / Process Automation and HTS Data Analysis - Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Germany

 

Wednesday - November 17, 2021

1st Session

09:30 - 10:45

Cheminformatics

Daniel Svozil

Institute of Molecular Genetics of the Czech Academy of Sciences (IMG), Czech Republic

10:45Break (15')

2nd Session

11:00 - 12:15

Probes & Drugs

Ctibor Skuta

Institute of Molecular Genetics of the Czech Academy of Sciences (IMG), Czech Republic

 

Thursday - November 18, 2021

1st Session

09:30 - 10:45

Medicinal chemistry

Ana Martinez

Head of the Translational Medicinal and Biological Chemistry group - Centro de Investigaciones Biológicas Margarita Salas (CSIC), Spain

10:45Break (15')

2nd Session

11:00 - 12:15

Fragment screening

Aigars Jirgensons

Head of Organic Synthesis Methodology group - Latvian Institute of Organic Synthesis (OSI), Latvia

12:15Lunch Break (105')

3rd Session

14:00 - 15:15

Target deconvolution by chemical proteomics

Guillaume Médard 

Group Leader Chemical Proteomics at Chair of Bioanalytics, TUM School of Life Sciences, Technical University of Munich, Germany

 

Friday - November 19, 2021

1st Session

09:30 - 10:45

Principles of open data and open source tools

Phil Gribbon

Head of Discovery Research - Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Germany  

10:45Break (15')

2nd Session

11:00 - 12:15

The European Chemical Biology Database (ECBD)

Tomas Muller

Institute of Molecular Genetics of the Czech Academy of Sciences (IMG), Czech Republic

12:15 - 12:30

Closing and Survey time for data reproducibility